October clarified size and timing for Depo-Provera cases, and the Judicial Panel on Multidistrict Litigation reports 6,412 actions in its October 1 docket count. Lawyers and Settlements reports registration closing November 30, with first payments expected in Q1 2027, in its settlement timeline update. Depo-Provera is the injectable form of medroxyprogesterone acetate at issue here. Meningioma is the brain-tumor diagnosis behind these claims.
The district court's MDL page identifies the cases as MDL No. 3140, centralized federal litigation before Judge M. Casey Rodgers. It places them in the Northern District of Florida after transfer on Feb. 7, 2025.
Official resources:
- Read the official notice from Uscourts — Use this primary source to verify the official announcement.
- Read the original report from Uscourts — Use this primary source to review the complete report.
Table of Contents
- How Large Is the Federal Litigation?
- What Does the Settlement Framework Cover?
- What Links Depo-Provera to Meningioma?
- What Should You Do Before November 30?
How Large Is the Federal Litigation?
The Judicial Panel on Multidistrict Litigation's Oct. 1, 2026 report lists 6,412 pending actions and 6,524 total historical actions in MDL 3140. Pending counts active cases, while the higher total reflects cases ever filed in the MDL.
Growth to this size helps explain why parties pursued a broad resolution structure. A pending inventory above 6,400 makes individual trial dates impractical for most plaintiffs. Centralized pretrial work lets one court set common deadlines and settlement procedures.
What Does the Settlement Framework Cover?
Miller & Zois Lawsuit Information Center's Oct. 7, 2026 update says Pfizer and plaintiffs' leadership reached an agreement in principle on June 15, 2026. The same update says the parties signed a confidential Master Settlement Agreement on July 21, 2026 covering the MDL and New York state cases. Lawyers and Settlements' Oct. 8, 2026 report estimates about 80% of current federal plaintiffs would be eligible.
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The same report places registration closing Nov. 30, 2026 with claims processing and first payments expected in Q1 2027. Atumio News' Sept. 27, 2026 report says Judge Rodgers appointed Matt Garretson as Allocation Master for the Supplemental Compensation Fund on Sept. 9, 2026. The same report names CPA Randall Sansom to administer the Qualified Settlement Fund, with BrownGreer as settlement administrator.
What Links Depo-Provera to Meningioma?
The BMJ published the 2024 French national case-control study of 18,061 meningioma-surgery cases and 90,305 controls in its French case-control analysis. It reported injectable medroxyprogesterone acetate odds ratio 5.55, 95% CI 2.27-13.56, driven by use of one year or more. An odds ratio above 1 means higher odds appeared in the longer-use group in that study.
The National Library of Medicine hosts the current DailyMed label for Depo-Provera CI with a section 5.4 meningioma warning. It directs monitoring for meningioma signs and stopping the drug if meningioma is diagnosed, reflecting FDA approval of the warning in Dec. 2025.
What Should You Do Before November 30?
Hissey Mulderig & Friend via JD Supra says payout tiers, proof rules and amounts remain confidential with no admission of wrongdoing. The same analysis says the Sept. 18, 2026 Rule 702 causation hearing and statute-of-limitations pilot cases affect only ineligible or non-settling claimants. It also warns unfiled claims still face deadlines.
Registration is the control point for potential settlement participation. Use these checks to avoid missing the window because of incomplete records. Do not wait for payment announcements to get records in order. Hissey Mulderig & Friend via JD Supra notes unfiled claims still face deadlines, so delay can narrow options.
- Gather pharmacy and clinic records that show when use started and stopped.
- Keep diagnosis, imaging and surgery reports together for legal review.
- Ask counsel if you are registered and what proof applies to your claim.
- Track the cutoff through counsel and save copies of everything submitted.
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